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Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

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Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
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Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

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Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
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Cardiopulmonary Resuscitation III: AED Use01:23

Cardiopulmonary Resuscitation III: AED Use

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Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Cardiomyopathy V: Interprofessional Care01:29

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Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
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Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

403
Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.
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Related Experiment Video

Updated: Feb 16, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

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Up-to-date cardiac resynchronization therapy.

Hideo Okamura1

  • 1National Cerebral and Cardiovascular Center Osaka Japan.

Journal of General and Family Medicine
|December 22, 2017
PubMed
Summary

Cardiac resynchronization therapy (CRT) improves heart failure prognosis and quality of life. Optimizing patient selection and lead placement is key for maximizing CRT benefits in heart failure patients.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Cardiac resynchronization therapy (CRT) has been available for over a decade for severe chronic heart failure.
  • Numerous studies confirm CRT enhances quality of life and patient prognosis.
  • CRT indications have broadened to include mild heart failure cases.

Purpose of the Study:

  • To review the efficacy and indications of cardiac resynchronization therapy (CRT).
  • To guide the selection of heart failure patients most likely to benefit from CRT.
  • To address challenges in CRT lead placement and patient selection.

Main Methods:

  • Review of existing literature on cardiac resynchronization therapy.
  • Analysis of studies demonstrating CRT efficacy and patient outcomes.
Keywords:
CRTcardiac resynchronization therapyindicationreview

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  • Discussion of anatomical and physiological limitations affecting CRT lead positioning.

    • Main Results:

    • CRT is proven to improve quality of life and prognosis in heart failure patients.
    • Expanded indications for CRT now include mild heart failure.
    • Patient selection and left ventricular lead placement remain critical factors for successful CRT outcomes.

    Conclusions:

    • Cardiac resynchronization therapy offers significant benefits for selected heart failure patients.
    • Further research and clinical practice should focus on optimizing CRT candidate selection and lead placement techniques.
    • Expanding appropriate use of CRT can improve outcomes for more heart failure patients.