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Published on: February 6, 2011
Blood Volume in Malignant Disease: Case Studies in 86 Females1
T S Reeve1, P C Vincent1, Nea Brittle1
1Department of Surgery, University of Sydney and Wellcome Laboratories for Experimental Medicine and Surgery, Institute for Medical Research, Royal North Shore Hospital of Sydney.
The problem of blood replacement in the individual cancer patient remains unanswered. On present evidence, such a patient must be assumed to be drawn from a population with a mean total blood volume and mean red-cell volume below normal and thus must be assumed to have a better-than-even chance of having a depleted volume. However, it does not necessarily follow that transfusion is necessary; this should ideally be assessed by blood volume determination in each individual case.
The problem of blood replacement in the individual cancer patient remains unanswered. On present evidence, such a patient must be assumed to be drawn from a population with a mean total blood volume and mean red-cell volume below normal and thus must be assumed to have a better-than-even chance of having a depleted volume. However, it does not necessarily follow that transfusion is necessary; this should ideally be assessed by blood volume determination in each individual case.

