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Metastatic Melanoma in the Small Bowel
W A A G Macbeth1, J F Gwynne1, M G Jamieson1
1Departments of Surgery and Pathology, University of Otago Medical School and Dunedin and Wakari Hospitals, Dunedin, New Zealand.
The Australian and New Zealand Journal of Surgery
|December 22, 2017
Summary
Metastatic melanoma in the small bowel is more common than previously thought. This study reviews seven cases, challenging its reputed rare incidence and discussing clinical features.
Area of Science:
- Gastroenterology
- Oncology
- Surgical Pathology
Background:
- Metastatic melanoma to the small bowel is considered a rare condition.
- Accurate incidence data and clinical presentation are not well-established.
Purpose of the Study:
- To challenge the perceived rarity of small bowel melanoma metastasis.
- To review clinical features and literature of this condition.
- To analyze the incidence of small bowel melanoma metastasis in relation to other small bowel neoplasms.
Main Methods:
- Case series review of seven patients with metastatic melanoma in the small bowel.
- Surgical resection in five cases; necropsy in two cases.
- Literature review on metastatic melanoma of the small bowel.
Main Results:
- Seven cases of small bowel metastatic melanoma were identified.
- Five patients underwent surgical resection; two cases were discovered during necropsy.
- The study suggests a higher incidence than commonly reported.
Conclusions:
- Metastatic melanoma to the small bowel may be underdiagnosed or more frequent than previously believed.
- Clinical features and diagnostic challenges warrant further investigation.
- Comparative incidence data provide context for small bowel neoplasms.
