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Herpes Zoster Optic Neuropathy.

Aaron R Kaufman1, Eileen M Myers, Mark L Moster

  • 1Boston University School of Medicine (ARK), Boston, Massachusetts; Department of Ophthalmology (EMM, KCG), University of Cincinnati, Cincinnati Eye Institute, Cincinnati, Ohio; Neuro-Ophthalmology Service (MLM), Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania; and Department of Ophthalmology (JS, LBK), University of Alabama School of Medicine, Birmingham, Alabama.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|December 22, 2017
PubMed
Summary
This summary is machine-generated.

Herpes zoster optic neuropathy (HZON) is a rare complication of HZO. Visual outcomes vary, and the role of corticosteroids in HZON treatment requires further investigation.

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Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Herpes zoster optic neuropathy (HZON) is a rare but distinct complication of herpes zoster ophthalmicus (HZO).
  • Understanding HZON's clinical profile is crucial for effective management.

Purpose of the Study:

  • To characterize the clinical features of HZON.
  • To evaluate therapeutic choices and visual outcomes in HZON patients.

Main Methods:

  • Retrospective chart review across multiple academic eye centers.
  • Inclusion criteria: optic neuropathy within 1 month of ipsilateral trigeminal dermatome zoster.
  • Data collected on presentation, treatment, and visual acuity.

Main Results:

  • Six HZON cases identified; mean follow-up 2.75 months.
  • HZON occurred mean 14.1 days post-rash; anterior in 2 eyes, retrobulbar in 4.
  • Visual acuity outcomes were variable; eyes without systemic corticosteroids showed better final acuity.

Conclusions:

  • HZON is an unusual complication of HZO with variable visual recovery.
  • Optimal HZON treatment regimen remains undetermined from this cohort.
  • Systemic antivirals are standard; corticosteroid efficacy is unclear and case-dependent.