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Updated: Feb 16, 2026
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Collecting And Measuring Wound Exudate Biochemical Mediators In Surgical Wounds
Published on: October 20, 2012
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Caesarean section wound infection surveillance: Information for action
Simon M Scheck1, Timothy Blackmore1, Dushyant Maharaj1,2
1Wellington Regional Hospital, Capital and Coast District Health Board, Wellington, New Zealand.
The Australian & New Zealand Journal of Obstetrics & Gynaecology
|December 22, 2017
Summary
Maternal obesity is a major risk factor for surgical site infection (SSI) after caesarean section. Optimizing antibiotic dosing and wound care for high-risk groups like obese women can significantly reduce SSI rates.
Area of Science:
- Obstetrics and Gynecology
- Infectious Disease Epidemiology
- Surgical Safety
Background:
- Surgical site infection (SSI) following caesarean section poses a significant morbidity risk.
- Maternal, procedural, and antibiotic factors are known contributors to wound infections.
Purpose of the Study:
- To clarify risk factors for caesarean section SSI and identify areas for improvement.
- To evaluate the effectiveness of adjusted antibiotic dosing and simplified surveillance techniques.
Main Methods:
- Retrospective cohort study of 2231 women undergoing caesarean section (2014-2015).
- Identified SSIs via culture-positive wound samples within 30 days.
- Calculated odds ratios for maternal, procedural, and antibiotic risk factors.
Main Results:
- Maternal obesity (BMI ≥ 30) was a significant SSI risk factor (OR 4.1).
- Increased cefazolin dose for obese women significantly reduced SSI (OR 0.309).
- Māori (OR 2.1) and Samoan (OR 3.0) women had increased SSI risk.
Conclusions:
- Elevated BMI is the primary risk factor for post-caesarean SSI.
- Targeted antibiotic dosing and specialized wound care are crucial for high-risk groups.
- Simplified surveillance methods can effectively identify trends in SSI.
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