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Updated: Feb 16, 2026

Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation
Published on: June 7, 2016
Stimulation and Neuromodulation in the Treatment of Epilepsy
Timothy Marc Eastin1, Miguel Angel Lopez-Gonzalez2
1Department of Neurosurgery, Loma Linda University, Loma Linda, CA 92354, USA. meastin@llu.edu.
Abstract:
Invasive brain stimulation technologies are allowing the improvement of multiple neurological diseases that were non-manageable in the past. Nowadays, this technology is widely used for movement disorders and is undergoing multiple clinical and basic science research for development of new applications. Epilepsy is one of the conditions that can benefit from these emerging technologies. The objective of this manuscript is to review literature about historical background, current principles and outcomes of available modalities of neuromodulation and deep brain stimulation in epilepsy patients.
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