Adenocarcinoma of the appendix

Area of Science:

• Gastroenterology
• Surgical Oncology
• Pathology

Background:

• Adenocarcinoma of the vermiform appendix is an uncommon malignancy.
• Diagnosis is often delayed, with presentation mimicking acute appendicitis.

Purpose of the Study:

• To review cases of appendiceal adenocarcinoma over a 15-year period.
• To assess the diagnostic and treatment patterns for this rare cancer.

Main Methods:

• Retrospective review of 11 cases of adenocarcinoma of the vermiform appendix.
• Analysis of patient demographics, clinical presentation, surgical management, and outcomes.

Main Results:

• 11 cases identified over 15 years (1 in 956 appendicectomies).
• One-third presented as acute appendicitis; only half of those initially undergoing appendectomy had subsequent hemicolectomy.
• Disease presented in a younger age group than typical colorectal cancers.

Conclusions:

• Histological examination of all appendectomy specimens is essential.
• Appendiceal adenocarcinoma may occur in younger patients, necessitating awareness beyond typical colorectal cancer demographics.