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An In Vitro Model for Studying Cellular Transformation by Kaposi Sarcoma Herpesvirus
Published on: August 25, 2017
Atypical Kaposi's sarcoma in young inmunocompetent patient
Josefa Sánchez-López1, Santiago Pérez-Parra2, María Librada Porriño-Bustamante3
1Department of Dermatology, Complejo Hospitalario La Mancha Centro, Alcázar de San Juan, Ciudad Real, Spain.
Abstract:
Kaposi´s sarcoma is a rare tumor associated with human herpes virus 8 (HHV-8) infection. Four main clinical subtypes have been described. This study reports on a form of KS in an HIV negative and immunocompetent middle-aged man. The only remarkable factor is that he has sex with other men. This form of Kaposi´s sarcoma is rare. It occurs more in younger patients than in the classic form, is limited to the skin, and is associated with a good prognosis. The means of transmission of the virus is through saliva in oroanal or orogenital sexual practices. Mechanisms of tumor development are still not well known. Given the possible increased number of this variant, it would be interesting to extend this study.
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