Epidemiology of Zika Virus Infection

Susan L Hills1, Marc Fischer1, Lyle R Petersen1

  • 1Division of Vector-Borne Diseases, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado.

Insights

Zika virus (ZIKAV) emerged from obscurity, causing widespread outbreaks in the Pacific, Americas, and Asia. This global spread highlights the urgent need for continued surveillance and understanding of ZIKAV transmission and its associated health risks.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Zika virus (ZIKAV) was historically endemic in Africa and Southeast Asia.
  • An Asian genotype ZIKAV outbreak in 2007 marked its emergence from obscurity.
  • Global spread led to significant outbreaks in the Pacific and Americas.

Purpose of the Study:

  • To document the emergence and global spread of Zika virus.
  • To highlight the scale of ZIKAV transmission and associated health concerns.
  • To underscore the importance of enhanced surveillance for emerging infectious diseases.

Main Methods:

  • Review of reported ZIKAV cases and outbreaks.
  • Analysis of ZIKAV spread across different geographical regions.
  • Monitoring of public health organization reports and surveillance data.

Main Results:

  • ZIKAV caused a major outbreak in the Pacific starting in 2013.
  • Over 750,000 suspected and confirmed cases reported in the Americas by March 2017.
  • Increased case recognition and birth defect reports in Southeast Asia, with 84 countries reporting ZIKAV transmission by April 2017.

Conclusions:

  • Zika virus (ZIKAV) represents a significant global public health threat.
  • The virus has demonstrated rapid geographic spread and potential for severe health outcomes.
  • Continued international surveillance and research are critical for managing ZIKAV.

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