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Production and Detection of Reactive Oxygen Species ROS in Cancers
Published on: November 21, 2011
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Antioxidants: Friend or foe?
R Sarangarajan1, S Meera2, R Rukkumani3
1Department of Oral Pathology, Madha Dental College, Kundrathur, Chennai, India.
Asian Pacific Journal of Tropical Medicine
|December 23, 2017
Summary
Oxidative stress from reactive oxygen species contributes to diseases. Antioxidants offer therapeutic benefits but also have detrimental effects, requiring careful consideration in disease treatment.
Area of Science:
- Biochemistry
- Pathology
- Pharmacology
Background:
- Reactive oxygen species (ROS) are metabolic byproducts neutralized by the body's antioxidant system.
- An imbalance leading to oxidative stress is linked to diseases like Alzheimer's, cardiovascular disorders, and cancer.
Purpose of the Study:
- To review the beneficial and detrimental effects of antioxidants in disease treatment.
- To compile evidence on antioxidant therapy for cancer, cardiovascular diseases, diabetes, and oral diseases.
Main Methods:
- Literature review of studies on antioxidant therapy.
- Analysis of research on the dual role of antioxidants in various pathologies.
Main Results:
- Antioxidants demonstrate therapeutic potential in managing several diseases.
- Evidence also highlights negative consequences associated with antioxidant use in certain conditions.
Conclusions:
- Antioxidant therapy presents a complex profile with both advantages and disadvantages.
- Further research is needed to optimize antioxidant use and mitigate potential harm in clinical applications.
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