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Reproducibility of apparent diffusion coefficient measurements evaluated with different workstations.

M Fanariotis1, K Vassiou2, I Tsougos3

  • 1Diagnostic Radiology Department, University of Thessaly, Biopolis, 41110, Larissa, Greece; Department of Radiology, Sykehuset Telemark HF, Ulefossvegen 55, 3710, Skien, Telemark, Norway.

Clinical Radiology
|December 23, 2017
PubMed
Summary
This summary is machine-generated.

Apparent diffusion coefficient (ADC) measurements for breast lesions are reproducible across different computer platforms. This finding suggests consistent post-processing of MRI data is achievable, enhancing diagnostic reliability.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Oncology

Background:

  • Apparent diffusion coefficient (ADC) measurements are crucial for characterizing breast lesions.
  • Variations in post-processing can affect ADC measurement reproducibility.
  • Standardizing ADC measurement across different platforms is essential for reliable diagnosis.

Purpose of the Study:

  • To evaluate the reproducibility of apparent diffusion coefficient (ADC) measurements for breast lesions.
  • To assess the influence of different computer platforms on ADC measurement consistency.
  • To address post-processing variability in breast MRI analysis.

Main Methods:

  • Prospective study including 100 biopsy-proven breast lesions.
  • 3 Tesla MRI with diffusion-weighted imaging (b-values 0 and 850 s/mm²).
  • ADC values measured on two platforms: MRI workstation and DICOM viewer; agreement assessed using ICC and Bland-Altman plots.

Main Results:

  • High agreement between workstation ADC measurements (ICC=0.981).
  • No systematic differences identified between platforms using Bland-Altman plots.
  • Narrow limits of agreement for ADC measurements across platforms.

Conclusions:

  • ADC measurements demonstrate high reproducibility between the evaluated computer platforms.
  • Post-processing influences on ADC measurement reproducibility are minimal with the tested platforms.
  • Findings support the reliability of ADC measurements for breast lesion characterization across different workstations.