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Updated: Feb 16, 2026

Formation of Human Prostate Epithelium Using Tissue Recombination of Rodent Urogenital Sinus Mesenchyme and Human Stem Cells
Published on: June 22, 2013
Mesonephric proliferations of the female genital tract
Brooke E Howitt1, Marisa R Nucci2
1Brigham and Women's Hospital, Department of Pathology, Division of Women's and Perinatal Pathology, Boston, MA, USA; Department of Pathology, Stanford School of Medicine, Stanford, CA, United States.
Abstract:
The mesonephric (Wolffian) duct regresses in females during embryological development. Remnants of this duct may persist typically along the lateral walls of the cervix, vagina, adnexa, and uterine corpus. These mesonephric epithelia may expand into hyperplastic proliferations and rarely form neoplasms. The spectrum of morphology, immunophenotype, clinical presentation, and molecular characteristics of mesonephric lesions is reviewed, with attention to distinction from entities in the differential diagnosis.
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