Related Experiment Video
Updated: Feb 16, 2026

A Modified Method for Intrathecal Catheterization in Rats
Published on: February 14, 2025
Colonic perforation by an intrathecal baclofen pump catheter causing delayed Escherichia coli meningitis
Oliver Patrick Devine1, Andrew Christopher Harborne2, William B Lo2
1University College London Medical School, London, UK.
Abstract:
Intrathecal baclofen (ITB) delivery via an implanted pump is frequently used for the treatment of spasticity. This is an effective and safe neurosurgical and pharmacological intervention associated with an improvement in patient quality of life. There is, however, a risk of device-related infection. We present a patient with pump-site infection and Escherichia coli meningitis secondary to transcolonic perforation of an intrathecal baclofen pump catheter. While this is rare, we review the intraoperative precautions and best practices that should be taken to prevent and manage this unusual complication.
More Related Videos
Related Concept Videos
Esophageal Perforation-I: Introduction
The location of esophageal perforation can vary, occurring anywhere along the esophagus....
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Esophageal Perforation-II: Clinical Manifestations and Management
Clinical Manifestations:
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Aneurysm IV: Nursing Management

