Related Experiment Video
Updated: Feb 16, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Development of a Cardiovascular Simulator for Studying Pulse Diagnosis Mechanisms
Min Jang1, Min-Woo Lee2, Jaeuk U Kim3
1Department of East-West Medical Engineering, Sangji University, Wonju 26339, Republic of Korea.
Abstract:
This research was undertaken to develop a cardiovascular simulator for use in the study of pulse diagnosis. The physical (i.e., pulse wave transmission and reflection) and physiological (i.e., systolic and diastolic pressure, pulse pressure, and mean pressure) characteristics of the radial pulse wave were reproduced by our simulator. The simulator consisted of an arterial component and a pulse-generating component. Computer simulation was used to simplify the arterial component while maintaining the elastic modulus and artery size. To improve the reflected wave characteristics, a palmar arch was incorporated within the simulator. The simulated radial pulse showed good agreement with clinical data.
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