Related Experiment Video
Updated: Feb 16, 2026
06:39
Biological Preparation and Mechanical Technique for Determining Viscoelastic Properties of Zonular Fibers
Published on: December 16, 2021
2.4K
Pregnancy and Marfan syndrome
1Heart Institute, Kaplan Medical Center, Rehovot, affiliated to Hebrew University, Jerusalem, Israel.
Annals of Cardiothoracic Surgery
|December 23, 2017
Summary
Pregnancy in women with Marfan syndrome (MFS) requires special care due to risks like aortic dissection. This review offers management recommendations for pregnant MFS patients.
Area of Science:
- Cardiology
- Obstetrics
- Genetics
Background:
- Marfan syndrome (MFS) is a genetic disorder affecting connective tissue.
- Pregnancy in women with MFS is associated with increased maternal and fetal risks.
- Aortic dissection is the primary cause of mortality in MFS patients.
Purpose of the Study:
- To review current clinical information on Marfan syndrome in pregnancy.
- To provide management recommendations for pregnant patients with MFS.
Main Methods:
- Extensive literature review of clinical information.
- Synthesis of existing data for management guidelines.
Main Results:
- Pregnancy exacerbates risks in MFS patients, particularly cardiovascular complications.
- Aortic dissection remains a critical concern during gestation.
- Multidisciplinary management is crucial for favorable outcomes.
Conclusions:
- Careful monitoring and management are essential for pregnant women with MFS.
- Early detection and intervention for cardiovascular issues can improve maternal and fetal health.
- This review provides a framework for optimizing care in this high-risk population.
More Related Videos
08:22A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene
Published on: September 16, 2019
8.5K
05:44Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
Published on: May 17, 2024
1.2K
Related Concept Videos
01:19Mitral Valve Prolapse III: Nursing Management
422
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
422
01:27Mitral Valve Prolapse I: Introduction
606
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
606
01:30Aneurysm I: Introduction
449
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
449
01:23Cystic Fibrosis: Pathogenesis
898
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
898
01:22Mitral Valve Prolapse II: Assessment and Management
694
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
694
01:07Teratogenicity
4.3K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
4.3K