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Prognostic value of serum phospholipase A in acute pancreatitis
M Büchler1, P Malfertheiner, H Schädlich
1Department of Surgery, University of Ulm, Federal Republic of Germany.
Klinische Wochenschrift
|February 1, 1989
Abstract:
Serum from 48 patients with acute pancreatitis (21 with interstitial-edematous and 27 with necrotizing pancreatitis) was monitored for immunoreactive (IR) phospholipase A2 (PLA2) protein concentration and PLA catalytic activity. In both groups within 48 h after start of acute pancreatitis an up to tenfold increase of IR-PLA2 was demonstrable. Determination of IR-PLA2 revealed no differences between the groups. In contrast, determination of PLA catalytic activity allowed us to differentiate between patients with interstitial-edematous and necrotizing pancreatitis.