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[Lichen nitidus and lichen striatus].

I Stolze1, H Hamm2

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Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 23, 2017
PubMed
Summary

Lichen nitidus and lichen striatus are rare skin conditions primarily affecting children. While lichen striatus typically resolves on its own, lichen nitidus management requires careful consideration of treatment options due to its chronic nature.

Keywords:
BlaschkitisBlaschko linesCalcineurin inhibitorsCorticosteroidsKoebner phenomenon

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Area of Science:

  • Dermatology
  • Pediatric Dermatology
  • Immunodermatology

Background:

  • Lichen nitidus is a rare, chronic skin condition presenting as small papules, often in children, with unclear pathogenesis involving immunologic and genetic factors.
  • Lichen striatus is an acquired dermatosis in preschool children, characterized by papules along Blaschko's lines, possibly due to immune reactions triggered by external factors.
  • Both conditions can be associated with other dermatoses or systemic diseases, and treatments must be carefully considered, especially given their typical course in young patients.

Purpose of the Study:

  • To differentiate between Lichen nitidus and Lichen Striatus.
  • To discuss the pathogenesis, clinical presentation, and treatment options for both conditions.
  • To emphasize the importance of conservative management in pediatric cases.

Main Methods:

  • Review of clinical presentations and histological patterns of Lichen nitidus.
  • Analysis of the assumed postzygotic mutation and immune response in Lichen Striatus.
  • Compilation of current therapeutic strategies and their indications for both dermatoses.

Main Results:

  • Lichen nitidus presents with pathognomonic histological findings and requires careful treatment weighing due to its chronic nature.
  • Lichen striatus typically resolves spontaneously within months, with therapies reserved for symptomatic cases like pruritus.
  • Nail involvement can occur in Lichen Striatus, and postinflammatory hypopigmentation may persist.

Conclusions:

  • Management of Lichen nitidus should balance potential side effects against therapeutic benefits.
  • Lichen striatus generally requires minimal intervention, focusing on symptomatic relief if needed.
  • Understanding the distinct characteristics and natural history of each condition is crucial for appropriate patient care.