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Inflammatory pseudotumor of the liver
S B Standiford1, H Sobel, K S Dasmahapatra
1Surgical Service, Veterans Administration Medical Center, East Orange, New Jersey.
Journal of Surgical Oncology
|April 1, 1989
Summary
Inflammatory pseudotumors, also known as plasma cell granulomas, are benign liver lesions that can mimic cancer. These rare liver masses typically resolve without complication, avoiding the need for surgery.
Area of Science:
- Hepatobiliary Medicine
- Surgical Pathology
- Oncology
Background:
- Inflammatory pseudotumors (plasma cell granulomas) are rare, benign lesions characterized by chronic inflammation and plasma cell predominance.
- These lesions can present in various organs but are most commonly found in the lung.
- While typically benign, their gross appearance can mimic malignant neoplasms, posing diagnostic challenges.
Observation:
- A 77-year-old male presented with constitutional symptoms including fever and malaise.
- Imaging revealed a liver lesion in the left lobe.
- Surgical exploration confirmed the lesion to be an inflammatory pseudotumor.
Findings:
- The liver lesion was histologically confirmed as an inflammatory pseudotumor, lacking evidence of anaplasia.
- This case adds to the limited number of reported inflammatory pseudotumors in the liver and biliary tract.
- The patient experienced an uneventful recovery, consistent with the benign nature of these lesions.
Implications:
- Inflammatory pseudotumors of the liver follow a benign clinical course.
- Surgical resection (hepatectomy) should be reserved for symptomatic cases due to mass effect or when a definitive preoperative diagnosis is unobtainable.
- Accurate preoperative or intraoperative diagnosis is crucial to avoid unnecessary aggressive surgical intervention.