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Management of pneumothorax in hemodynamically stable preterm infants using high frequency oscillatory ventilation:
Claudia Aurilia1, Cinzia Ricci1, Milena Tana1
1Division of Neonatology, Department for the protection of women's health and the nascent life, child and adolescent, Fondazione Policlinico Universitario A. Gemelli-Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168, Rome, Italy.
Insights
High-frequency oscillatory ventilation offers a safe, conservative approach for managing pneumothorax in preterm infants. This method successfully treated air leaks without requiring chest tube insertion, minimizing associated risks.
Area of Science:
- Neonatal Medicine
- Pediatric Respiratory Medicine
- Critical Care
Background:
- Pneumothorax is a frequent complication in preterm infants despite advances in ventilation.
- Managing air leaks in neonates presents significant clinical challenges.
- Conservative expectant management for air leaks in stable preterm infants has shown promise.
Purpose of the Study:
- To evaluate the efficacy of high-frequency oscillatory ventilation (HFOV) in treating pneumothorax in preterm infants.
- To assess the feasibility of avoiding chest tube insertion in these cases.
Main Methods:
- Retrospective case series of five preterm infants (birth weight ≤ 1250g) with respiratory distress syndrome.
- Initial treatment with nasal continuous positive airway pressure (nCPAP).
- Intubation and treatment with HFOV for worsening respiratory distress and pneumothorax, without chest tube drainage.
Main Results:
- All five preterm infants with pneumothorax were successfully managed with HFOV.
- This approach avoided the need for chest tube insertion.
- No increase in air leak or associated complications were observed.
Conclusions:
- HFOV provides a viable conservative management strategy for significant pneumothorax in hemodynamically stable preterm newborns requiring mechanical ventilation.
- This HFOV strategy can effectively prevent worsening air leaks and the need for chest tube drainage, thereby avoiding associated risks.
Background:
Despite an increased use of non-invasive ventilatory strategies and gentle ventilation, pneumothorax remains a common complication in preterm infants. The ventilator management of infants with air leaks remains challenging in terms of both prevention and treatment. Recently the safety and efficacy of expectant management avoiding chest tube drainage to treat large air leak in preterm infants hemodynamically stable has been reported.
Case Presentation:
In the present study, we report five cases of preterm infants with birth weight ≤ 1250 g affected by respiratory distress syndrome and treated with nasal continuous positive airway pressure as first intention. They were intubated for worsening of respiratory distress with increasing oxygen requirement and concomitant increase of respiratory rate and PCO2 values due to occurrence of pneumothorax, and they were successfully treated using high-frequency oscillatory ventilation without chest tube insertion.
Conclusion:
In our experience high-frequency oscillatory ventilation provided a conservative management of a significant pneumothorax in preterm newborns hemodynamically stable and requiring mechanical ventilation. This approach allowed us to avoid the increasing of air leak and the insertion of chest tube drainage and all the subsequent associated risks.
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