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[Epidemiology of pancreatic cancer]
Antoine Drouillard1, Sylvain Manfredi1, Côme Lepage1
1Registre Bourguignon des cancers digestifs, Inserm U866, université de Bourgogne, CHU de Dijon, université de Bourgogne, registre Bourguignon des cancers digestifs, Inserm U866, 21000 Dijon, France; Centre hospitalo-universitaire Dijon-Bourgogne, service d'hépato-gastroentérologie et d'oncologie digestive, 21000 Dijon, France.
Abstract:
Actually, pancreatic cancer is a major challenge in digestive oncology. Its prognosis remains very poor with a five-year net survival less than 10%. Although if pancreatic cancer incidence was low, data from French digestive cancer registries show a dramatic increase in recent years, more marked in women (annual variation of +3.6% between 1982 and 2012) than in men (+2.3%). The currently recognized risk factors like tobacco or obesity cannot explain this evolving epidemiology. Moreover, progress in understanding pancreatic carcinogenesis is still insufficient. Except for familial aggregation, systematic screening couldn't be proposed.
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