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Related Concept Videos

Epilepsy and Seizures: Overview01:24

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
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A Model for Epilepsy of Infectious Etiology using Theiler's Murine Encephalomyelitis Virus
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[Psychiatric comorbidities in epilepsy].

Bertrand de Toffol1, Coraline Hingray2, Julien Biberon3

  • 1Inserm U 930, CHU Bretonneau, service de neurologie et neurophysiologie clinique, 2 bis, boulevard Tonnellé, 37044 Tours cedex, France.

Presse Medicale (Paris, France : 1983)
|December 25, 2017
PubMed
Summary
This summary is machine-generated.

Epilepsy patients frequently experience psychiatric issues like depression and anxiety. These conditions can be effectively managed with antidepressants (SSRIs), which are safe for epilepsy patients.

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Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Neuroscience

Background:

  • Epilepsy is frequently associated with psychiatric comorbidities, exceeding general population rates.
  • A bidirectional relationship exists between epilepsy and psychiatric disorders.
  • Epilepsy-related psychiatric symptoms exhibit distinct patterns based on seizure timing (interictal, preictal, postictal).

Purpose of the Study:

  • To highlight the prevalence of psychiatric comorbidities in epilepsy.
  • To discuss the specific nature of psychiatric symptoms in epilepsy patients.
  • To review assessment tools and treatment options for psychiatric disorders in epilepsy.

Main Methods:

  • Utilized existing literature review on epilepsy and psychiatric comorbidities.
  • Examined the characteristics of psychiatric symptomatology relative to seizure phases.
  • Identified validated self-administered questionnaires for assessing depression (NDDI-E) and anxiety (GAD-7).

Main Results:

  • Psychiatric comorbidities are significantly more common in individuals with epilepsy.
  • The timing of psychiatric symptoms (interictal, preictal, postictal) is characteristic in epilepsy.
  • Validated tools like NDDI-E and GAD-7 enable efficient symptom assessment.
  • Selective serotonin reuptake inhibitors (SSRIs) demonstrate safety and efficacy in treating these comorbidities.

Conclusions:

  • Effective management strategies exist for psychiatric comorbidities in epilepsy.
  • SSRIs offer a safe and effective treatment option for depressive and anxiety disorders in epilepsy patients.
  • Early identification and treatment of psychiatric symptoms are crucial for improving patient outcomes.