Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Testosterone: Functions and Regulation

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...

Overview of the Cardiovascular System

Overview of the Cardiovascular System

The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...

Regulation of the Cardiovascular System

Regulation of the Cardiovascular System

The regulation of the cardiovascular system allows the body to adapt to various demands and maintain homeostasis.
The regulation of the cardiovascular system involves the autonomic nervous system (ANS), baroreceptors, and chemoreceptors, ensuring that heart rate and blood pressure are appropriately modulated in response to varying physiological demands.
The ANS comprises two main divisions: the sympathetic and parasympathetic nervous systems. The sympathetic nervous system enhances...

Health Literacy

Health Literacy

Health literacy is an individual's or a community's capacity to comprehend, receive, read, and use relevant healthcare information and services. The World Health Organization (WHO, 2018) defines health literacy as the cognitive and social skills that determine the ability of individuals to gain access to, understand, and use information in ways that promote and maintain good health. As a result, the WHO helps individuals manage long-term health concerns, participate in preventative...

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Assessment of the Cardiovascular System II: Inspection

Assessment of the Cardiovascular System II: Inspection

Inspection is the initial step in assessing the cardiovascular system. It involves a detailed visual examination that provides crucial information about a patient's circulatory and cardiac health. This systematic process, conducted from head to toe, helps identify signs of cardiovascular conditions by observing physical appearance, skin and mucous membranes, jugular and carotid pulsations, chest symmetry, and the condition of the extremities.
Head and Neck

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Peak myocardial work assessment to detect coronary ischemia during dobutamine stress echocardiography.

Frontiers in cardiovascular medicine·2025

Same author

Omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases.

Progress in cardiovascular diseases·2024

Same author

Estrogen and cardiovascular disease.

Progress in cardiovascular diseases·2024

Same author

Omega 3, Atrial Fibrillation, and Cardiovascular Outcomes.

Journal of the American College of Cardiology·2023

Same author

Testosterone and cardiovascular health.

European heart journal·2023

Same author

Hormones and COVID-19.

Mayo Clinic proceedings·2023

Search research articles

Related Experiment Video

Updated: Feb 16, 2026

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

Testosterone and Cardiovascular Health.

Andrew Elagizi¹, Tobias S Köhler², Carl J Lavie³

¹Department of Internal Medicine, Leonard J. Chabert Medical Center, Houma, LA.

Mayo Clinic Proceedings

|December 25, 2017

Summary

The link between testosterone and cardiovascular health remains debated. Current evidence suggests testosterone therapy

More Related Videos

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

Related Experiment Videos

Last Updated: Feb 16, 2026

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Combining Behavioral Endocrinology and Experimental Economics: Testosterone and Social Decision Making

Published on: March 2, 2011

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis

Published on: September 26, 2018

In Silico Clinical Trials for Cardiovascular Disease

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

Area of Science:

Endocrinology
Cardiology
Medical Research

Background:

Conflicting evidence exists on testosterone's impact on cardiovascular disease (CVD).
Concerns about testosterone therapy risks led to FDA warnings, despite flawed supporting studies.
Medical expert groups question the scientific basis of some FDA statements on testosterone therapy.

Purpose of the Study:

To review current evidence on the relationship between endogenous and supplemental testosterone and cardiovascular health.
To clarify the ongoing debate regarding testosterone's effects on cardiovascular outcomes.

Main Methods:

A literature review was performed using PubMed and key cardiology journals.
Search terms included testosterone, cardiovascular health, coronary artery disease, heart failure, and androgen deprivation therapy.
Studies published between January 1, 2007, and December 31, 2016, were prioritized, with key older publications included for historical context.

Main Results:

The review synthesizes evidence on testosterone's complex association with cardiovascular health.
Identifies flaws in studies that initially raised concerns about testosterone therapy and CVD events.

Conclusions:

The relationship between testosterone levels (endogenous and supplemental) and cardiovascular health requires careful consideration.
Further research and nuanced understanding are needed to address the ongoing debate and guide clinical practice.