Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Factorial Design

Factorial Design

Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...

Amyloid Fibrils

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A New Definition of an Acupuncture Meridian.

Journal of acupuncture and meridian studies·2018

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 16, 2026

Visualizing Motion Patterns in Acupuncture Manipulation

Visualizing Motion Patterns in Acupuncture Manipulation

Published on: July 16, 2016

A Curious Oversight in Acupuncture Research.

Fletcher Kovich¹

¹Curepoint Acupuncture Practice, Bristol, United Kingdom.

Journal of Acupuncture and Meridian Studies

|December 26, 2017

Summary

Existing acupuncture hypotheses fail to explain its effects by overlooking key phenomena. This research identifies these overlooked aspects and proposes future investigation methods for a comprehensive understanding of acupuncture mechanisms.

Keywords:

acupuncture electrical wave semiconduction signal propagation

More Related Videos

Acupuncture in a Rat Model of Asthma

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

Author Spotlight: Development of a Standardized Acupuncture Tool Inspired by Advanced Techniques for Improved Safety and Precision

Author Spotlight: Development of a Standardized Acupuncture Tool Inspired by Advanced Techniques for Improved Safety and Precision

Published on: January 10, 2025

Related Experiment Videos

Last Updated: Feb 16, 2026

Visualizing Motion Patterns in Acupuncture Manipulation

Visualizing Motion Patterns in Acupuncture Manipulation

Published on: July 16, 2016

Acupuncture in a Rat Model of Asthma

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

Author Spotlight: Development of a Standardized Acupuncture Tool Inspired by Advanced Techniques for Improved Safety and Precision

Author Spotlight: Development of a Standardized Acupuncture Tool Inspired by Advanced Techniques for Improved Safety and Precision

Published on: January 10, 2025

Area of Science:

Integrative Medicine
Neuroscience
Physiology

Background:

Current hypotheses on acupuncture mechanisms are incomplete.
Key phenomena integral to acupuncture's effects have been neglected.
This gap limits the scientific understanding of acupuncture.

Purpose of the Study:

To identify overlooked phenomena in acupuncture research.
To propose avenues for future investigation into acupuncture's efficacy.
To refine existing hypotheses on how acupuncture works.

Main Methods:

Literature review of existing acupuncture hypotheses.
Analysis of common acupuncture practices and their physiological correlates.
Identification of discrepancies between observed effects and theoretical explanations.

Main Results:

Specific sensory and physiological phenomena central to acupuncture were identified as overlooked.
These include factors like needle manipulation techniques and patient-specific responses.
Existing models do not adequately incorporate these elements.

Conclusions:

Revising acupuncture hypotheses to include overlooked phenomena is crucial.
Future research should focus on investigating these neglected aspects.
A more complete understanding of acupuncture's therapeutic effects can be achieved.