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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
Published on: June 21, 2018
Yasbanoo Moayedi1, Juan G Duero Posada1, Gillian C Nesbitt2
1Division of Medicine, Department of Cardiology, University of Toronto, Toronto, Ontario, Canada; Ted Rogers Centre of Excellence in Heart Function, Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
Providing clinical history before bedside echocardiography improves diagnostic accuracy only if it is concordant. Discordant information before testing significantly reduces accuracy, suggesting post-test history may be superior for accurate diagnosis.
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