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Anti-angiogenic effects of biotechnological therapies in rheumatic diseases
Francesco Paolo Cantatore1, Nicola Maruotti1, Addolorata Corrado1
1Rheumatology Clinic, Department of Medical and Surgical Sciences, University of Foggia Medical School, Foggia.
Introduction:
Angiogenesis plays a key role in the pathogenesis of numerous rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and vasculitides. Therefore, the inhibition of pathological angiogenesis may be considered a useful therapeutical approach in these rheumatic diseases.
Methods:
This review article is based on a literature research about the role of biotechnological therapies in angiogenesis inhibition.
Results And Conclusions:
Several evidences have demonstrated a role for biotechnological therapies in angiogenesis inhibition. Nevertheless, further research and clinical trials are needed to better quantify the real impact of biotechnological therapies on pathological angiogenesis.
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