Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Induced-fit Model01:13

Induced-fit Model

89.7K
Most chemical reactions in cells require enzymes—biological catalysts that speed up the reaction without being consumed or permanently changed. They reduce the activation energy needed to convert the reactants into products. Enzymes are proteins, that usually work by binding to a substrate—a reactant molecule that they act upon.
Enzymes exhibit substrate specificity, meaning that they can only bind to certain substrates. This is mainly determined by the shape and chemical...
89.7K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

28.2K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
28.2K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

5.7K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
5.7K
Induced Electric Dipoles01:28

Induced Electric Dipoles

4.9K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.9K
Induced Electric Fields01:23

Induced Electric Fields

4.7K
The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...
4.7K
Spontaneous and Induced Mutations01:30

Spontaneous and Induced Mutations

2.4K
Spontaneous mutations arise infrequently during DNA replication due to errors in the process. A key factor behind these errors is tautomeric shifts in nitrogenous bases, where bases transition from keto to enol forms or amino to imino forms. This shift can alter base-pairing rules, leading to mutations. Additionally, reactive oxygen species (ROS) arising from aerobic metabolism can damage DNA, resulting in depurination (loss of a purine base) or depyrimidination (loss of a pyrimidine base).
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An Exploratory LC-HRMS Metabolomics Study of Culture Medium-Dependent Metabolic Variation and Bioactivity in Ten Fungal Strains.

International journal of molecular sciences·2026
Same author

Levodopa-Induced dyskinesia in Latin America: Prevalence and associated clinical factors in the LARGE-PD cohort.

Journal of Parkinson's disease·2026
Same author

Paenitracins, a novel family of bacitracin-type nonribosomal peptide antibiotics produced by plant-associated <i>Paenibacillus</i> species.

mSystems·2026
Same author

Aspiration Versus Stent-Retriever as First-Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity-Score Matched Multicenter Analysis.

Stroke (Hoboken, N.J.)·2026
Same author

Ex Vivo Thrombus Magnetic Resonance Imaging Features and Patient Clinical Data Enable Prediction of Acute Ischemic Stroke Cause.

Stroke (Hoboken, N.J.)·2026
Same author

Argentine Consensus on the Diagnosis of Dementia. Part One: Introduction, Methodology, Current Scenario, and Diagnostic Algorithms

Vertex (Buenos Aires, Argentina)·2026
Same journal

Pallidal Deep Brain Stimulation in Dystonia: Investigating Differential Response by Dystonia Distribution.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same journal

Essential Tremor and Digital Biomarkers: A Scoping Review Using the TRACE Framework to Map Readiness for Clinical Trials and Routine Practice.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same journal

Effects of Focal Low-Energy Extracorporeal Shock Wave Treatment (ESWT) as an Add-On to Botulinum Toxin (BoNT) Injection on Pisa Syndrome in Parkinson's Disease.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same journal

Longitudinal Intention Tremor Trajectories in Essential Tremor: A Comment.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same journal

Immediate and Short-Term Effects of Multimodal Neuromodulatory Rehabilitation Following Thalamotomy for Writer's Cramp: A Case Report.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
Same journal

Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy for Essential Tremor in a Patient with an Arteriovenous Malformation.

Tremor and other hyperkinetic movements (New York, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Feb 16, 2026

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
09:54

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: April 18, 2019

14.6K

Sertraline-induced Hemichorea.

Emilia M Gatto1, Victoria Aldinio1, Virginia Parisi1

  • 1Department of Neurology, Sanatorio de la Trinidad Mitre, Buenos Aires, Argentina.

Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|December 26, 2017
PubMed
Summary
This summary is machine-generated.

This case report details a rare instance of hemichorea, a movement disorder, linked to sertraline, a selective serotonin reuptake inhibitor. The patient

Keywords:
Hemichoreachoreahemichoreaselective serotonin reuptake inhibitorssertraline

More Related Videos

In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells
06:01

In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells

Published on: December 3, 2020

6.3K
Environmentally Induced Heritable Changes in Flax
08:10

Environmentally Induced Heritable Changes in Flax

Published on: January 26, 2011

10.6K

Related Experiment Videos

Last Updated: Feb 16, 2026

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells
09:54

Generation of 3D Skin Organoid from Cord Blood-derived Induced Pluripotent Stem Cells

Published on: April 18, 2019

14.6K
In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells
06:01

In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells

Published on: December 3, 2020

6.3K
Environmentally Induced Heritable Changes in Flax
08:10

Environmentally Induced Heritable Changes in Flax

Published on: January 26, 2011

10.6K

Area of Science:

  • Neurology
  • Pharmacology
  • Movement Disorders

Background:

  • Hemichorea-hemiballism is a syndrome with diverse causes.
  • Drug-induced hemichorea is a rare adverse effect associated with selective serotonin reuptake inhibitors (SSRIs).
  • No prior reports linked sertraline to hemichorea.

Observation:

  • A 65-year-old female developed hemichorea within one week of starting sertraline.
  • Comprehensive investigations ruled out other potential etiologies for the movement disorder.
  • The hemichorea resolved after discontinuing sertraline treatment.

Findings:

  • The temporal relationship and negative workup strongly suggested sertraline-induced hemichorea.
  • The patient's presentation represents a novel association between sertraline and hemichorea.
  • Exclusion of other causes supports a drug-induced etiology.

Implications:

  • This case highlights a potential, albeit rare, adverse effect of sertraline.
  • Enhanced serotonergic activity in the basal ganglia may underlie sertraline-induced hemichorea.
  • Clinicians should consider SSRI-induced movement disorders in differential diagnoses.