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Updated: Feb 16, 2026

Mouse Models for Graft Arteriosclerosis
Published on: May 14, 2013
Late Disruption of a Polyethylene Terephthalate Aortic Graft 30 Years after Initial Graft Placement
Akihito Matsushita1, Yu Tsunoda1, Takashi Hattori1
1Department of Cardiovascular Surgery, Seikeikai Chiba Medical Centre, Chiba, Japan.
Abstract:
A 71 year old male who had undergone extra-anatomic bypass grafting between the ascending aorta and the thoraco-abdominal aorta at 41 years of age for aortic coarctation was admitted with back pain and dyspnea. A 16 mm Cooley double velour knitted polyethylene terephthalate (PET) graft was used in the initial operation in 1983. Computed tomography showed disruption of the initial PET graft perforating the right atrium, and a pseudoaneurysm at the distal anastomosis. The patient was in acute cardiac failure because of left to right shunting. A two stage operation was performed. The first stage comprised emergency re-grafting and right atrium repair, and the second stage re-grafting for the pseudoaneurysm. The patient is doing well 48 months post-operatively; however, monitoring of the patient will continue for potential PET graft rupture.
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