The long-term neurodevelopmental outcomes of infants born full-term with low birth weight

Ayşe Tosun1, Börte Gürbüz-Özgür2, Hatice Aksu3

  • 1Departments of Pediatric Neurology, Adnan Menderes University Faculty of Medicine, Aydın.

Insights

Infants born small for gestational age (SGA) may experience long-term neurodevelopmental challenges. These include delayed milestones, lower IQ, and increased ADHD symptoms, impacting school success and behavior.

Area of Science:

  • Pediatrics
  • Neurodevelopment
  • Child Psychology

Background:

  • Small for gestational age (SGA) infants are born at or after 37 weeks with birth weights below the tenth percentile.
  • Long-term neurodevelopmental outcomes in SGA children require further investigation.

Purpose of the Study:

  • To evaluate the long-term neurological development, school success, intelligence quotient (IQ), and attention deficit hyperactivity disorder (ADHD) symptoms in children born SGA.
  • To compare these outcomes with a healthy control group.

Main Methods:

  • A cohort of 74 SGA children and 75 healthy controls were assessed by child neurologists and psychiatrists.
  • Standardized assessments included the Wechsler Intelligence Scale for Children-Revised, Ankara Developmental Screening Inventory, and T-DSM-IV-S.

Main Results:

  • SGA children showed shorter breastfeeding duration, later walking and talking, and more vision disorders.
  • SGA cases had higher incidence of febrile convulsions, delayed mental development, lower school success, and higher ADHD diagnosis rates.
  • SGA children exhibited lower scores on inattention and conduct disorder subscales of the T-DSM-IV-S.

Conclusions:

  • Being born small for gestational age (SGA) is associated with negative long-term impacts on a child's behavior, attention, and academic achievement.
  • Early identification and intervention may be crucial for mitigating these developmental challenges in SGA populations.

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