Related Experiment Video
Updated: Feb 16, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Pulmonary Sarcoidosis in a patient with Multiple Sclerosis on daclizumab monotherapy
Elijah Edward Rhone1, Peter Siu Pan Cho2, Surinder S Birring2
1Department of Neurology, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
Abstract:
As new immunomodulatory therapies continue to be licensed for use in Multiple Sclerosis, it is important to remain vigilant for new, unexpected associations relating to these medications. We highlight this by reporting on a case of a 45-year-old man who developed systemic, non-specific symptoms following long term use of daclizumab and was subsequently diagnosed with sarcoidosis. We go on to briefly discuss the action of daclizumab, in particular the effect it has on CD56bright natural killer cells, a cell type that has been investigated in relation to sarcoidosis.
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