Related Experiment Video
Updated: Feb 16, 2026

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
Published on: March 11, 2017
The relationship between the S-wave in lead 1 and recurrence of RVOT PVC ablation
Hacı Murat Güneş1, Gültekin Günhan Demir1, Oğuz Karaca1
1Medipol University Faculty of Medicine, Cardiology Department, Istanbul, Turkey.
Background:
Radiofrequency catheter ablation (CA) is a common non-pharmacological treatment option for ventricular premature contractions (PVCs) originating from right ventricular outflow tract (RVOT). In this study, we aimed to investigate the relationship between recurrence after CA for RVOT-PVC and S-wave in lead 1 that was shown to be associated with RVOT depolarization.
Methodology:
A total of 104 patients who were referred to our clinic for CA for idiopathic RVOT-PVC between 2012 and 2015years were enrolled. All ECG parameters were measured before and after the ablation procedure.
Results:
Ablation was successful in 100 patients (96,1%). These patients with successful ablation were followed for a mean duration of 1078days. 13 patients (13%) had recurrence. Univariate logistic regression analysis revealed age (odds ratio: 1.916, p:0,012), presence of post-procedural S1 (odds ratio:1.040 p:0,028), post-procedural S1 area (oddsratio:1.023 p:0,041), ΔS1 area (odds ratio:1.242 p:0,004) as predictors for recurrence. Multivariate logistic regression analysis detected age (odds ratio:1.053 p:0,032) and ΔS1 area (odds ratio:0.701 p:0,009) as predictors for recurrence.
Conclusion:
Radiofrequency CA for RVOT-PVC can be performed with high procedural success and low complication rates. Age and ΔS1 area might be helpful for prediction of recurrence after CA.
Related Concept Videos
Relationship Formation
The Wave Nature of Light
Ending Relationships
Pharmacokinetic–Pharmacodynamic Relationship: Duration of Dose-Effect Relationship
Relationship Growth
Pharmacokinetic–Pharmacodynamic Relationship: Intensity of Dose-Effect Relationship

