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Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides

Magdalena Slusarczyk1, Salvatore Ferla1, Andrea Brancale1

  • 1School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, King Edward VII Avenue, Cardiff CF10 3NB, UK.

Bioorganic & Medicinal Chemistry
|December 27, 2017
PubMed

Keywords:
AnticancerHuman Hint enzymeNucleoside analogue (NA)Orotidine-5′-monophosphate decarboxylase (ODCase)Phosphoramidate (ProTide) approach

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