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Updated: Feb 16, 2026
05:48
Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands
Published on: January 2, 2018
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Retrospective evaluation of notched QRS complexes in dogs: 85 cases
1Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Auburn University, 1220 Wire Road, Auburn, AL 36849, USA.
Summary
Notched QRS complexes on electrocardiography (ECG) can occur in dogs with or without heart disease. However, if notched QRS complexes appear in more than one ECG lead, it significantly increases the likelihood of underlying cardiac disease.
Area of Science:
- Veterinary Cardiology
- Canine Electrocardiography
Background:
- Notched QRS complexes on ECG are an understudied finding in veterinary medicine.
- Previous reports exist in human and veterinary literature, but specific data on canine patients is limited.
Purpose of the Study:
- To characterize signalment and cardiac diagnoses in dogs exhibiting notched QRS complexes.
- To detail the ECG leads and the number of leads affected by notched QRS complexes.
Main Methods:
- Retrospective analysis of 85 dogs with notched QRS complexes on at least one ECG lead.
- Review of digital ECGs and medical records from routine clinical evaluations.
Main Results:
- The average age of dogs with notched QRS complexes was 9.15 years.
- 69.4% of dogs with notched QRS complexes had diagnosed cardiac disease.
- A significantly higher odds ratio (3.97) for cardiac disease was observed when notched QRS complexes were present in more than one ECG lead.
Conclusions:
- Notched QRS complexes can be present in dogs regardless of cardiac health.
- The presence of notched QRS complexes in multiple ECG leads strongly suggests underlying cardiac disease and warrants further investigation.
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