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IgG4-related disease with possible myocardial involvement
Josefa López Vivancos1, Lluís Sanchez Sitges1, Xavier Herranz Perez1
1Servicio de Medicina Interna, Hospital Universitari General de Catalunya, Universitat Internacional de Catalunya, Sant Cugat del Vallés, Barcelona, España.
Reumatologia Clinica
|December 27, 2017
Summary
Immunoglobulin G4-related disease (IgG4-RD) can affect the heart, a previously undescribed manifestation. Cardiac magnetic resonance imaging detected possible myocardial involvement in a patient with IgG4-related disease.
Area of Science:
- Cardiology
- Immunology
- Pathology
Background:
- Immunoglobulin G4-related disease (IgG4-RD) is a multisystemic condition characterized by specific histopathological findings.
- While IgG4-RD can affect various organs, myocardial involvement has not been previously documented in the medical literature.
Observation:
- This case report details a male patient diagnosed with IgG4-related disease.
- Cardiac magnetic resonance imaging revealed potential involvement of the heart muscle.
Findings:
- The findings suggest that myocardial involvement is a possible, albeit rare, manifestation of IgG4-related disease.
- The imaging findings necessitate consideration of IgG4-RD in the differential diagnosis of cardiac conditions.
Implications:
- Accurate diagnosis is crucial as IgG4-related disease requires specific treatment strategies.
- Distinguishing IgG4-related cardiac involvement from other conditions like sarcoidosis and Fabry disease is vital for appropriate patient management and therapeutic impact.
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