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Updated: Feb 16, 2026

Digital PCR for Quantifying Circulating MicroRNAs in Acute Myocardial Infarction and Cardiovascular Disease
Published on: July 3, 2018
IgG4-related disease with possible myocardial involvement
Josefa López Vivancos1, Lluís Sanchez Sitges1, Xavier Herranz Perez1
1Servicio de Medicina Interna, Hospital Universitari General de Catalunya, Universitat Internacional de Catalunya, Sant Cugat del Vallés, Barcelona, España.
Abstract:
IgG4-related disease is characterized by mass lesions, a dense lymphoplasmacytic infiltrate with immunohistochemical positivity for IgG4, storiform fibrosis and, frequently, elevated serum IgG4 levels. It can be multisystemic; however, myocardial involvement, which is objectively determined by imaging tests, has not been described in the medical literature. We report the case of a man with IgG4-related disease with possible myocardial involvement, detected by cardiac magnetic resonance. This raises the question of a differential diagnosis with other diseases such as sarcoidosis and Fabry disease, the differential diagnosis of which is of great importance due to its therapeutic impact.
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