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IMTBX and Grppr: Software for Top-Down Proteomics Utilizing Ion Mobility-Mass Spectrometry

Dmitry M Avtonomov1, Daniel A Polasky1, Brandon T Ruotolo1

  • 1Department of Pathology, ‡Department of Chemistry, and §Department of Computational Medicine and Bioinformatics, University of Michigan , Ann Arbor, Michigan United States.

Analytical Chemistry
|December 27, 2017
PubMed
Summary

New software, IMTBX and Grppr, enables automated analysis of complex top-down proteomics data from ion mobility mass spectrometry. This advances protein sequencing and post-translational modification analysis.

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