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Cystic placentomegaly on a second-trimester ultrasound

Heather P Adams1, Jennifer Malloy

  • 1Heather P. Adams is an assistant professor at Gannon University in Erie, Pa., and practices in women's health. Jennifer Malloy is a graduate of the PA program at Gannon University and practices in endocrinology. The authors have disclosed no potential conflicts of interest, financial or otherwise.

JAAPA : Official Journal of the American Academy of Physician Assistants
|December 27, 2017
PubMed

Placental mesenchymal dysplasia (PMD) is a rare disorder of the placenta characterized by placentomegaly, cystic vesicles, and dilated chorionic blood vessels. Clinically and pathologically, it closely resembles partial molar pregnancy and complete hydatidiform mole with a coexistent healthy fetus, both of which are associated with malignant trophoblastic disease. PMD, however, has no risk of malignant trophoblastic disease and can result in the birth of a normal fetus, highlighting the need for clinician awareness of PMD in order to avoid unnecessary termination of a viable and potentially healthy fetus.

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