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Intermittent intraocular thrombin as an adjunct to vitrectomy
D P Maxwell1, M E Orlick, J G Diamond
1Tulane University School of Medicine, Department of Ophthalmology, New Orleans, LA.
Ophthalmic Surgery
|February 1, 1989
Summary
Intraocular thrombin effectively controls bleeding during eye surgery for trauma and diabetic retinopathy. Intermittent boluses offer better control over intraocular pressure and dosage compared to continuous infusion.
Area of Science:
- Ophthalmology
- Surgical Hemostasis
Background:
- Intraoperative hemorrhage poses significant risks in ocular surgeries.
- Managing bleeding in severe ocular trauma and proliferative diabetic retinopathy presents unique challenges.
Observation:
- Two cases utilizing intraocular thrombin for hemorrhage control are presented.
- The study focuses on severe ocular trauma and proliferative diabetic retinopathy.
Findings:
- A technique using intermittent boluses of 100 units/ml thrombin in BSS Plus solution was employed.
- This method demonstrated advantages over constant infusion, allowing precise control of intraocular pressure and thrombin delivery.
Implications:
- This modified gravity infusion technique offers a simple and effective approach to managing intraocular bleeding.
- It provides surgeons with enhanced control during complex ophthalmic procedures.