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Updated: Feb 16, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
Maternal cytoglobin (CYGB) serum levels in normal and preeclamptic pregnancies
Ahter Tanay Tayyar1, Ahmet Tayyar2, Sukran Kozali1
1a Department of Obstetrics and Gynecology , Health Sciences University, Zeynep Kamil Maternity and Children's Training and Research Hospital , İstanbul , Turkey.
Objective:
To investigate cytoglobin levels in women with preeclampsia and women with uncomplicated pregnancies.
Materials And Methods:
A cross-sectional study including 26 pregnant women complicated with early-onset preeclampsia (EO-PE) and 26 pregnant women complicated with late-onset preeclampsia (LO-PE) were recruited for the study group. Twenty-seven healthy pregnant women selected randomly were included in the control group. The serum CYGB concentrations were measured using an enzyme-linked immunosorbent assay.
Results:
Gestational age at delivery and mean birth weight were significantly lower in the preeclampsia groups than in the control group and were found to be the lowest in the EO-PE group (p < .001). Serum CYGB levels were significantly higher in the EO-PE and LO-PE groups as compared with the control group (9.99 (6.08) ng/ml (EOPE), 10.04 (7.04) ng/ml (LOPE) versus 2.84 (0.82) ng/ml), (p < .001). However, a significant difference was not found between the EO-PE and LO-PE groups regarding CYGB levels (p = 1.000).
Conclusions:
Serum CYGB levels were significantly higher in patients with EO-PE and LO-PE as compared to healthy pregnant women.
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