Anger and aggression treatments: a review of meta-analyses

Amy Hyoeun Lee1, Raymond DiGiuseppe1

  • 1Department of Psychology, St. John's University, 8000 Utopia Pkwy, Queens, NY 11439, United States.

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Directing Effect of Substituents: meta-Directing Groups

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All meta-directing substituents are deactivating groups. These substituents withdraw electrons from the aromatic ring, making the ring less reactive toward electrophilic substitution. For example, the nitration of nitrobenzene is 100,000 times slower than that of benzene because of the deactivating effect of the nitro group. The first step in an electrophilic aromatic substitution is the addition of an electrophile to form a resonance-stabilized carbocation. The energy diagrams for...
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