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Asthma Screening in Pediatric Sickle Cell Disease: A Clinic-Based Program Using Questionnaires and Spirometry.

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Asthma screening in children with sickle cell disease (SCD) identified many with asthma or lung issues. However, few referred patients completed pulmonary clinic evaluations, highlighting a gap in care for this high-risk group.

Keywords:
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Area of Science:

  • Pulmonary Medicine
  • Pediatrics
  • Hematology

Background:

  • Asthma diagnosis in sickle cell disease (SCD) is linked to worse health outcomes.
  • Effective screening is needed to identify children with SCD who have asthma.

Purpose of the Study:

  • To assess the effectiveness of a screening program for identifying asthma in children with SCD.
  • To evaluate the utility of a questionnaire and spirometry in this population.

Main Methods:

  • A single-center project screened 157 children with SCD using the Breathmobile questionnaire and portable spirometry.
  • Participants with positive screening results were referred to a pediatric pulmonary clinic.

Main Results:

  • 37% of participants had a positive asthma screening questionnaire.
  • 34% of those tested had abnormal spirometry results.
  • Only 22% of referred patients were evaluated in the pulmonary clinic.

Conclusions:

  • Clinic-based screening effectively identifies asthma and pulmonary abnormalities in children with SCD.
  • Significant barriers exist in connecting referred patients with necessary pulmonary care.
  • Further research is needed to determine the impact of improved screening and management on pulmonary morbidity in SCD.