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Updated: Feb 16, 2026

Creation of Colonic Anastomosis in Mice
Published on: January 17, 2019
First cephalosomatic anastomosis in a human model
Xiaoping Ren1,2,3,4, Ming Li1,2,3, Xin Zhao1,2,3
1Hand and Microsurgical Center, 2 Affiliated Hospital, Harbin Medical University, Harbin, China.
Background:
Cephalosomatic anastomosis (CSA) has never been attempted before in man as the transected spinal cords of the body donor and body recipient could not be "fused" back together. Recent advances made this possible. Here, we report on the surgical steps necessary to reconnect a head to a body at the cervical level.
Methods:
Full rehearsal of a CSA on two recently deceased human cadavers was performed at Harbin Medical University, Harbin, China.
Results:
The surgery took 18 hours to complete within the time frame planned for this surgery. Several advances resulted from this rehearsal, including optimization of the surgical steps, sparing of the main nerves (phrenics, recurrent laryngeal nerves), and assessment of vertebral stabilization.
Conclusion:
Several specialties are involved in a full-scale CSA, including neck surgery, vascular surgery, orthopedic surgery, plastic surgery, gastrointestinal surgery, and neurosurgery, as well as the operating staff. This rehearsal confirmed the surgical feasibility of a human CSA and further validated the surgical plan. Education and coordination of all the operating teams and coordination of the operative staff was achieved in preparation for the live human CSA.
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