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Current treatment paradigms in pediatric short bowel syndrome

Raghav Chandra1, Anil Kesavan2

  • 1Doctor of Medicine (MD) Program, Rush Medical College, 600 S. Paulina St, Chicago, IL, 60612, USA.

Clinical Journal of Gastroenterology
|December 28, 2017
PubMed

Insights

Pediatric short bowel syndrome (SBS) is a severe condition in children requiring treatment for survival. Management aims to improve nutrient absorption and reduce reliance on parenteral support.

Area of Science:

  • Pediatric gastroenterology
  • Intestinal rehabilitation

Background:

  • Pediatric short bowel syndrome (SBS) is a critical condition caused by reduced small intestine length.
  • It leads to malabsorption, fluid/electrolyte imbalances, and growth failure, proving fatal without intervention.

Purpose of the Study:

  • To review current medical and surgical management strategies for pediatric SBS.
  • To discuss methods for achieving enteral autonomy and minimizing parenteral support dependence.

Main Methods:

  • Literature review of medical and surgical interventions for pediatric SBS.
  • Discussion of pharmacologic agents, nutrition, surgical procedures, and transplantation.

Main Results:

  • The review covers diverse treatment modalities for SBS.
  • Emphasis is placed on increasing the absorptive capacity of the remaining intestine.

Conclusions:

  • Effective management of pediatric SBS is crucial for improving outcomes.
  • Restoring enteral autonomy is the primary goal to reduce long-term parenteral support.

Keywords:
Intestinal adaptationIntestinal rehabilitationPediatric short bowel syndromeSmall bowel transplantationSurgical lengthening procedures

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