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Subcutaneous immunoglobulin for the treatment of deep morphoea in a child
M A Yamazaki-Nakashimada1, M Saez-de-Ocariz2, G Maldonado-Colin2
1Department of Clinical Immunology, Instituto Nacional Pediatría, Mexico City, Mexico.
Abstract:
Morphoea, also known as localized scleroderma, is a disorder characterized by excessive collagen deposition leading to thickening of the dermis and/or subcutaneous tissues. Intravenous IgG therapy has induced improvement in some fibrotic conditions. The primary indication for subcutaneous IgG (SCIG) is in primary immunodeficiency disorders as replacement therapy; however, recently there has been considerable interest in SCIG as an immunomodulatory agent. We report an 11-year-old girl with deep morphoea who was successfully treated with SCIG.
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