Related Experiment Video
Updated: Feb 16, 2026
04:59
Using a Knee Arthrometer to Evaluate Tissue-specific Contributions to Knee Flexion Contracture in the Rat
Published on: November 9, 2018
7.1K
Microbial Evaluation in Capsular Contracture of Breast Implants.
Marilena Galdiero1,2, Fabio Larocca1,2, Maria Rosaria Iovene1,2
1Naples, Italy.
Plastic and Reconstructive Surgery
|December 28, 2017
Summary
Bacterial biofilm formation on breast implants increases capsular contracture risk. This study links microbial contamination to implant complications, suggesting personalized antibiotic therapy to prevent reoperation.
Area of Science:
- Plastic Surgery
- Microbiology
- Biomaterials Science
Background:
- Capsular contracture is a frequent complication of breast implants, often necessitating reoperation.
- Subclinical infections and bacterial biofilm formation are implicated in capsular contracture development.
Purpose of the Study:
- To investigate the correlation between bacterial contamination and biofilm formation in mammary implants.
- To identify risk factors associated with capsular contracture in patients undergoing breast augmentation or reconstruction.
Main Methods:
- Microbiological assessment of bacterial flora from breast skin, nipple-areola complex, and mammary gland biopsy specimens.
- Comparison of microbial cultures from periprosthetic capsules and prosthesis surfaces.
- Study included 65 female patients undergoing breast plastic surgery in Naples, Italy.
Main Results:
- A higher incidence of capsular contracture was observed in oncologic patients who received radiotherapy.
- Patients with prior capsular contracture and cutaneous contamination by biofilm-producing microbes showed increased risk.
- Microbial contamination and biofilm production were correlated with implant contracture.
Conclusions:
- Despite advancements in surgical techniques, residual bacterial contamination is unavoidable.
- Preventative, personalized antibiotic therapy is recommended to mitigate the risk of capsular contracture.
- Understanding microbial involvement is crucial for improving breast implant outcomes.
Related Concept Videos
01:29Microbial Morphologies
4.2K
Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
4.2K
01:23Microbial Fermentation
1.6K
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
1.6K
01:28Microbial Nutrition
1.5K
Organisms exhibit remarkable metabolic diversity, categorized based on how they acquire energy and carbon. These strategies enable survival in various ecological niches and are essential for maintaining energy flow and nutrient cycling within ecosystems.Energy and Carbon SourcesOrganisms are classified as phototrophs or chemotrophs based on energy acquisition. Phototrophs use light as their energy source, while chemotrophs rely on oxidizing chemical compounds. Further differentiation arises...
1.5K
01:24Microbial Classification System
1.3K
Classification is the process of organizing organisms into hierarchically inclusive groups based on their phenotypic similarities or evolutionary relationships. A species comprises one or more strains, and closely related species are grouped into genera. Genera are further classified into families, families into orders, orders into classes, and so forth, up to the domain level, which is the broadest taxonomic rank derived from a combination of phenotypic and genotypic data.The nomenclature of...
1.3K
01:27Microbial Growth Media
2.4K
Microbial growth media are essential tools in microbiology, providing the nutrients and conditions necessary to cultivate and study microorganisms. These media are categorized by their composition, consistency, and functional roles, enabling researchers to investigate microbial physiology, behavior, and interactions.Types and Consistencies of Growth MediaGrowth media can be solid, liquid, or semisolid. Solid media, often agar-based, allow visible colony growth for isolation and enumeration.
2.4K
01:29Methods for Controlling Microbial Growth
1.8K
Microbial growth control refers to various methods employed to inhibit, reduce, or eliminate microorganisms to ensure safety and hygiene across different settings. These methods are categorized based on the target environment and the level of microbial control required.Biocides are versatile agents designed to control microorganisms by either inhibiting their growth or outright killing them. These agents work through various physical, chemical, mechanical, or biological mechanisms. The...
1.8K