Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

48.5K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.5K
Convergent Evolution01:54

Convergent Evolution

33.1K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
33.1K
Eukaryotic Evolution01:24

Eukaryotic Evolution

42.5K
The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
42.5K
Synteny and Evolution02:31

Synteny and Evolution

3.8K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.8K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of Cardiovascular Surgery in Patients With Multiple Sclerosis.

JAMA surgery·2026
Same author

Optimal Management for Moderate Aortic Stenosis at Time of Coronary Artery Bypass Grafting.

The Annals of thoracic surgery·2026
Same author

Validation of current mortality risk prediction models in patients with cirrhosis undergoing cardiac surgery.

JTCVS open·2026
Same author

Predictors and Outcomes of Nonvariceal Upper Gastrointestinal Bleed After Coronary Artery Bypass Grafting: A Nationwide Analysis.

Journal of the American Heart Association·2026
Same author

Representativeness in coronary revascularization trials: Beyond demographics.

JTCVS open·2026
Same author

Randomized Controlled Trial of the Psychological and Clinical Outcomes of Reiki Plus Manual Therapy After Open Heart Surgery.

The Journal of cardiovascular nursing·2026

Related Experiment Video

Updated: Feb 16, 2026

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation
05:08

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

2.3K

CABG: A continuing evolution.

Faisal Bakaeen1

  • 1Department of Thoracic and Cardiovascular Surgery, Heart & Vascular Institute, Cleveland Clinic, Cleveland, OH, USA. bakaeef@ccf.org.

Cleveland Clinic Journal of Medicine
|December 28, 2017
PubMed
Summary
This summary is machine-generated.

Coronary artery bypass grafting (CABG) is standard for complex lesions. Ongoing debates and new minimally invasive techniques are refining CABG

More Related Videos

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

10.1K
Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
09:00

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

12.4K

Related Experiment Videos

Last Updated: Feb 16, 2026

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation
05:08

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

2.3K
Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

10.1K
Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
09:00

Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Published on: May 2, 2018

12.4K

Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Medical Technology

Background:

  • Coronary artery bypass grafting (CABG) use is increasing due to new clinical trial data.
  • CABG remains the gold standard treatment for patients with complex coronary artery lesions.
  • Significant debate persists regarding optimal surgical techniques and graft choices in CABG.

Purpose of the Study:

  • To review the current status and evolving landscape of coronary artery bypass grafting (CABG).
  • To highlight key areas of ongoing debate in CABG procedures.
  • To discuss the impact of recent technological advancements on CABG risk-benefit profiles.

Main Methods:

  • Literature review of recent clinical trials and surgical technique advancements in CABG.
  • Analysis of comparative effectiveness for various graft conduits and harvesting methods.
  • Evaluation of emerging technologies such as minimally invasive surgery, robotics, and hybrid revascularization.

Main Results:

  • Clinical trials reaffirm CABG as the standard of care for complex coronary lesions.
  • Established debates include endoscopic vs. open vein harvesting, single vs. bilateral internal mammary artery grafts, and radial vs. saphenous vein grafts.
  • Newer approaches like minimally invasive surgery, robotics, and hybrid revascularization are altering patient selection and outcomes.

Conclusions:

  • Coronary artery bypass grafting (CABG) remains a critical intervention for complex coronary artery disease.
  • Technological innovations are expanding options and potentially improving outcomes for CABG patients.
  • Further research is needed to optimize graft selection and surgical approaches in the evolving field of cardiac revascularization.