Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Language01:16

Language

924
Language is a unique communication system that uses words and systematic rules to organize and transmit information. Unlike other forms of communication, which may involve postures, movements, odors, or vocalizations, language relies on symbols and grammar. This makes human communication distinct from that of other species, who also communicate but do not use language in the same way humans do.
Corballis and Suddendorf (2007) and Tomasello and Rakoczy (2003) highlight the role of language in...
924
pH Scale02:41

pH Scale

80.6K
Hydronium and hydroxide ions are present both in pure water and in all aqueous solutions, and their concentrations are inversely proportional as determined by the ion product of water (Kw). The concentrations of these ions in a solution are often critical determinants of the solution’s properties and the chemical behaviors of its other solutes. Two different solutions can differ in their hydronium or hydroxide ion concentrations by a million, billion, or even trillion times. A common means of...
80.6K
Components of Language01:24

Components of Language

836
Language, whether spoken, signed, or written, consists of specific components: lexicon and grammar. The lexicon is the vocabulary of a language, comprising its words. Grammar is the set of rules used to convey meaning through the lexicon. For example, English grammar adds “-ed” to most verbs to indicate past tense. Words are formed by combining phonemes, which are the basic sound units of a language. Different languages have different sets of phonemes (e.g., “ah” vs.
836
Language Development01:22

Language Development

956
Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
956
Language and Cognition01:27

Language and Cognition

820
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
820
Scaling01:26

Scaling

604
In designing and analyzing filters, resonant circuits, or circuit analysis at large, working with standard element values like 1 ohm, 1 henry, or 1 farad can be convenient before scaling these values to more realistic figures. This approach is widely utilized by not employing realistic element values in numerous examples and problems; it simplifies mastering circuit analysis through convenient component values. The complexity of calculations is thereby reduced, with the understanding that...
604

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modeling epithelial deformation and cell rearrangement in response to external forces during Zebrafish epiboly.

NPJ systems biology and applications·2026
Same author

Who's afraid of synthetic data? Hybrid approaches to deliver medical digital twins.

Informatics in medicine unlocked·2026
Same author

From FAIR to CURE: guidelines for computational models of biological systems.

NPJ systems biology and applications·2026
Same author

V-Cornea: A computational model of corneal epithelium homeostasis, injury, and recovery.

PLoS computational biology·2025
Same author

Surrogate modeling of Cellular-Potts agent-based models as a segmentation task using the U-Net neural network architecture.

PLoS computational biology·2025
Same author

Generative diffusion model surrogates for mechanistic agent-based biological models.

Machine learning: science and technology·2025
Same journal

A SIMULATION-OPTIMIZATION APPROACH TO IMPROVE THE ALLOCATION OF SECURITY SCREENING RESOURCES IN AIRPORT TERMINAL CHECKPOINTS.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2025
Same journal

Trajectory-oriented optimization of stochastic epidemiological models.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2025
Same journal

DISTRIBUTED MODEL EXPLORATION WITH EMEWS.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2025
Same journal

DESIGN AND DEPLOYMENT OF A SIMULATION PLATFORM: CASE STUDY OF AN AGENT-BASED MODEL FOR YOUTH SUICIDE PREVENTION.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2025
Same journal

TOWARDS A VIRTUAL FACTORY PROTOTYPE.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2024
Same journal

USING DISCRETE-EVENT SIMULATION TO FIND WAYS TO REDUCE PATIENT WAIT TIME IN A GLAUCOMA CLINIC.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference·2024
See all related articles

Related Experiment Video

Updated: Feb 16, 2026

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

831

TOWARDS A MULTI-SCALE AGENT-BASED PROGRAMMING LANGUAGE METHODOLOGY.

Endre Somogyi1, Amit Hagar2, James A Glazier3

  • 1Dept. of Computer Science, Biocomplexity Institute, Indiana University, Bloomington, IN 47405, USA.

Proceedings of the ... Winter Simulation Conference. Winter Simulation Conference
|December 29, 2017
PubMed
Summary
This summary is machine-generated.

We introduce the Continuous Concurrent Object Process Methodology (CCOPM), a novel executable modeling language for simulating complex living tissues. CCOPM naturally describes tissue dynamics, enabling visual agent-based model creation and computer simulation.

More Related Videos

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

4.6K
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
05:19

Practical Methodology of Cognitive Tasks Within a Navigational Assessment

Published on: June 1, 2015

14.1K

Related Experiment Videos

Last Updated: Feb 16, 2026

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans
08:14

Ecotoxicological Methodologies to Evaluate Biomarkers at Different Scales in Neotropical Anurans

Published on: April 28, 2023

831
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

4.6K
Practical Methodology of Cognitive Tasks Within a Navigational Assessment
05:19

Practical Methodology of Cognitive Tasks Within a Navigational Assessment

Published on: June 1, 2015

14.1K

Area of Science:

  • Computational Biology
  • Systems Biology
  • Bioinformatics

Background:

  • Living tissues are dynamic, heterogeneous systems with complex interactions between objects like cells and molecules.
  • Existing programming languages struggle to model the simultaneous, conditional, and hierarchical processes inherent in tissue dynamics.
  • Current modeling languages often lack the ability to translate models into executable simulations.

Purpose of the Study:

  • To present a new hybrid executable modeling language paradigm, the Continuous Concurrent Object Process Methodology (CCOPM).
  • To enable natural expression and visual creation of agent-based tissue models.
  • To facilitate computer simulation of these complex biological models.

Main Methods:

  • Development of the Continuous Concurrent Object Process Methodology (CCOPM) as a hybrid executable modeling language.
  • Designing CCOPM to naturally express complex relationships, hierarchical compositions, and dynamic processes within tissues.
  • Enabling visual creation of agent-based tissue models.

Main Results:

  • CCOPM successfully addresses the limitations of traditional programming languages in modeling tissue dynamics.
  • The methodology allows for the natural representation of heterogeneous objects and their concurrent, conditional processes.
  • Users can visually create agent-based tissue models using CCOPM.

Conclusions:

  • CCOPM provides a powerful new tool for modeling and simulating living tissues.
  • This executable modeling language paradigm bridges the gap between conceptual modeling and computational simulation.
  • CCOPM facilitates a deeper understanding of tissue organization and dynamics through agent-based modeling.