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Interventions for Nongenital Molluscum Contagiosum in Persons Without Immune Deficiency
Johannes C van der Wouden1, Sander Koning2, Kenneth A Katz3
1Department of General Practice and Elderly Care Medicine, Amsterdam Public Health Research Institute, VU University Medical Center Amsterdam, Netherlands.
Clinical Question:
How effective and safe are treatments for nongenital molluscum contagiosum in persons without immune deficiency?
Bottom Line:
Compared with placebo, imiquimod, 5%, cream was not more effective in clearing molluscum contagiosum and caused more local adverse effects, including application site reactions, in children aged 2 to 12 years; because high-quality evidence for other interventions is lacking, allowing for natural resolution of the infection remains a reasonable approach.
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