[Risk factors for multiple level osteoporosis vertebral compression fractures]
Shun-Xin Lin, Xiao-Bing Jiang, Geng-Yang Shen
1Department of Spinal Orthopaedics, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong, China; 7319890789@qq.com.
Spinal deformity index (SDI) and bone mineral density (BMD) are key risk factors for multiple level osteoporosis vertebral compression fractures (OVCFs). These findings help identify patients at higher risk for severe spinal issues.
Area of Science:
- Orthopedics
- Radiology
- Gerontology
Background:
- Osteoporosis is a prevalent condition leading to vertebral compression fractures (OVCFs).
- Multiple level OVCFs represent a more severe manifestation, necessitating identification of associated risk factors.
Purpose of the Study:
- To identify risk factors associated with multiple level osteoporosis vertebral compression fractures (OVCFs).
Main Methods:
- A cohort of 199 osteoporotic patients were classified into multiple level OVCFs and single level OVCF groups.
- Multivariate logistic regression analysis was employed to determine risk factors for multiple level OVCFs.
Main Results:
- No significant differences were observed in age, gender, BMI, hypertension, or diabetes between the groups.
- Multiple level OVCFs were significantly associated with spinal deformity index (SDI) and bone mineral density (BMD).
- Specific SDI ranges (2<=SDI<4 and SDI>=-4) and low BMD (T<-4.5SD) showed increased odds ratios for multiple level OVCFs.
Conclusions:
- Spinal deformity index (SDI) and bone mineral density (BMD) are identified as potential risk factors for multiple level OVCFs.
- These factors can aid in stratifying patients at higher risk for severe osteoporotic vertebral fractures.
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