[Research and progress on diagnosis and treatment of intervertebral space infection]

Xiao-Long Zhu, Wei-Xin Xu1, Jie Liu

  • 1Department of Orthopaedics, Tongde Hospital of Zhejiang Province, Hangzhou 310012, Zhejiang, China; xwx.spine@163.com.

Insights

Intervertebral disc infections are increasing post-surgery, making early diagnosis challenging. Improved diagnostic methods and tailored treatments are crucial for better patient outcomes in spinal infections.

Area of Science:

  • Spinal surgery
  • Infectious diseases

Background:

  • The increasing prevalence of disc surgery has led to a rise in intervertebral space infections.
  • Early diagnosis of these infections is often difficult due to a lack of specificity, increasing the risk of misdiagnosis.

Observation:

  • Microorganism culture from intervertebral disc puncture is the gold standard for antibiotic selection, but its positive detection rate requires improvement.
  • Current approaches to epidemiology, treatment, and surgical interventions for intervertebral infections vary significantly across medical institutions.

Findings:

  • Advanced imaging techniques like MRI and PET-CT, along with minimally invasive procedures such as percutaneous endoscopic debridement and lavage drainage, offer new avenues for diagnosis and treatment.
  • A multidisciplinary approach considering physician expertise and patient-specific factors is essential for selecting appropriate antibiotic treatments and surgical strategies.

Implications:

  • Greater emphasis on prevention, early pathogen identification, and timely diagnosis of intervertebral infections is warranted.
  • Close monitoring of laboratory indices and adaptive treatment adjustments are vital for optimizing patient recovery and minimizing complications.

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