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05:21
In Vivo Confocal Microscopy: A Standard Operating Procedure for the Detection of Demodex Mites at the Eyelid Margin
Published on: July 3, 2025
897
Demodex and rosacea: Is there a relationship?
Diana Gonzalez-Hinojosa1, Alejandro Jaime-Villalonga1, Gustavo Aguilar-Montes1
1Department of Ophthalmology, Hospital General Gea Gonzalez, Calzada de Tlalpan 4800, México.
Indian Journal of Ophthalmology
|December 29, 2017
Summary
Demodex mites are significantly more common on eyelashes of patients with rosacea. This finding highlights rosacea as a risk factor for Demodex infestation, particularly in the papulopustular subtype.
Area of Science:
- Ophthalmology
- Dermatology
- Microbiology
Background:
- Rosacea is a common chronic inflammatory skin condition.
- Demodex mites are frequently found on facial skin and in eyelash follicles.
- The association between Demodex and rosacea requires further investigation.
Purpose of the Study:
- To compare the frequency of Demodex infestation in the eyelash follicles of patients with rosacea versus individuals without rosacea.
- To determine if rosacea is a risk factor for Demodex infestation.
Main Methods:
- A comparative, observational, cross-sectional study.
- 41 patients with rosacea and 41 controls were included.
- Eyelashes were examined under a light microscope for Demodex presence.
Main Results:
- Demodex was found in 58.5% of rosacea patients (24/41) compared to 19.5% of controls (8/41).
- A statistically significant association (P ≤ 0.001) was observed between rosacea and Demodex infestation.
- The papulopustular subtype of rosacea showed a higher prevalence of Demodex.
Conclusions:
- Rosacea is a significant risk factor for Demodex infestation of the eyelashes.
- Early diagnosis and treatment of Demodex may be beneficial for rosacea patients.
- Further research into the pathogenic role of Demodex in rosacea is warranted.
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